Anti-ASIC2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ASIC2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:58kDa
Formulation
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Liquid in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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40
Uniprot ID
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Q16515
Background
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This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.
Research Area
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Synonyms
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ACCN; BNC1; MDEG; ACCN1; BNaC1; ASIC2a; hBNaC1; ASIC2