Anti-ASB2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ASB2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:70kDa
Formulation
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Liquid in PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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51676
Uniprot ID
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Q96Q27
Background
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This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Area
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Synonyms
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ASB-2; ASB2