Anti-ARAP2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ARAP2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:193kDa
Formulation
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Liquid in PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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116984
Uniprot ID
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Q8WZ64
Background
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The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.
Research Area
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Signal Transduction
Synonyms
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PARX; CENTD1; ARAP2