Anti-APOC2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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APOC2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/100-1/500
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:11kDa
Formulation
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Liquid in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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344
Uniprot ID
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P02655
Background
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This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.
Research Area
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Cardiovascular
Synonyms
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APO-CII; APOC-II; APOC2