Anti-AP3D1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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AP3D1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:130kDa
Formulation
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Liquid in PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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8943
Uniprot ID
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O14617
Background
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The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome.
Research Area
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Neuroscience
Synonyms
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ADTD; HPS10; hBLVR; AP3D1