Anti-AP1B1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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AP1B1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human AP1B1
Molecular Weight
-
-
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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162
Uniprot ID
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Q10567
Background
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Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Research Area
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Signal Transduction
Synonyms
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ADTB1; BAM22; AP105A; CLAPB2