Anti-ANKS1B Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ANKS1B
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:138kDa
Formulation
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Liquid in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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56899
Uniprot ID
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Q7Z6G8
Background
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This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Research Area
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Neuroscience
Synonyms
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EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2; ANKS1B