Anti-Angiotensin Converting Enzyme 1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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Ace
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-9E3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Recombinant protein of mouse Angiotensin Converting Enzyme 1
Molecular Weight
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Calculated MW: 151 kDa; Observed MW: 180 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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11421
Uniprot ID
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P09470
Background
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Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.
Research Area
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Cardiovascular
Synonyms
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ACE; Dipeptidyl carboxypeptidase I; Kininase II