Anti-Angiopoietin 1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ANGPT1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-1F9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Angiopoietin 1
Molecular Weight
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Calculated MW: 58 kDa; Observed MW: 75 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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284
Uniprot ID
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Q15389
Background
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Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.
Research Area
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Cancer
Synonyms
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ANGPT1; KIAA0003; Angiopoietin-1; ANG-1