Anti-alpha Actinin 4 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ACTN4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-2J3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human alpha Actinin 4
Molecular Weight
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Calculated MW: 105 kDa; Observed MW: 105 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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81
Uniprot ID
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O43707
Background
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F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
Research Area
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Signal Transduction
Synonyms
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actinin 4; Actinin alpha 4; actinin4; ACTN 4; Alpha-actinin-4; F actin cross linking protein; Focal segmental glomerulosclerosis 1; FSGS1; Non muscle alpha actinin 4