Anti-ALDH1L1 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ALDH1L1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN43
Isotype
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IgG2b
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Full length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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10840
Uniprot ID
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O75891
Background
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The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Research Area
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Neuroscience
Synonyms
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FDH; FTHFD; 10-FTHFDH; Cytosolic 10-formyltetrahydrofolate dehydrogenase