Anti-AFP Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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AFP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-4V-3
Isotype
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IgG
Reactivity
Application
Application Details
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WB：1/500-1/1000，IHC-P：1/50-1/100，ICC/IF：1/50，FC：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 69 kDa; Observed MW:69 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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174
Uniprot ID
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P02771
Background
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AFP is a major plasma protein expressed at high concentrations during fetal development; however, concentrations decrease drastically after birth. AFP is reactivated by approximately 80% of HCC. Like PSA, levels of serum AFP are an important diagnostic tool for detection of HCC. When hepatocytes regenerate or proliferate, AFP concentrations may increase. Elevated AFP concentrations may be observed in cirrhotic patients, during a flare-up of chronic hepatitis, or during the recovery phase postacute hepatitis. Additionally, AFP is commonly used as a tumor marker for hepatocellular carcinoma (HCC) or germ cell (nonseminoma) carcinoma.
Research Area
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Cell Biology
Synonyms
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HPAFP