Anti-Activin Receptor Type IIB Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ACVR2B
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-2I1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Activin Receptor Type IIB/ACVR2B
Molecular Weight
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Calculated MW: 58 kDa; Observed MW: 58 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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93
Uniprot ID
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Q13705
Background
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On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Research Area
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Signal Transduction
Synonyms
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ActR IIB; ACVR 2B; HTX4