Anti-ABCB5 (8D2) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ABCB5
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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8D2-2B8-4E8
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200
Immunogen
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Synthetic Peptide of ABCB5
Molecular Weight
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Calculated MW: 139 kDa; Observed MW: 90 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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340273
Uniprot ID
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Q2M3G0
Background
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Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Research Area
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Signal Transduction
Synonyms
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ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5