Anti-AASS Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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AASS
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/50-1/200 IHC: 1/50-1/100
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:102kDa
Formulation
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Liquid in PBS with 0.05% proclin300,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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10157
Uniprot ID
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Q9UDR5
Background
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This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
Research Area
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-
Synonyms
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AASS; LKR/SDH; LKRSDH; LORSDH; aminoadipate-semialdehyde synthase