Anti-4E BP3 (3B6) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
- 
          
            EIF4EBP3
          
 
Host
Storage
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            Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          
 
Clonality
Clone Number
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            3B6-D3-H7
          
 
Isotype
- 
          
            IgG1
          
 
Reactivity
Application
Application Details
- 
          
            WB: 1/500-1/1000  
          
 
Immunogen
- 
          
            Recombinant protein of human EIF4EBP3.
          
 
Molecular Weight
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            Calculated MW: 11 kDa; Observed MW: 11 kDa
          
 
Formulation
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            Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
          
 
Form
- 
          
            Liquid
          
 
Gene ID
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            8637
          
 
Uniprot ID
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            O60516
          
 
Background
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            Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation.
          
 
Research Area
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            Epigenetics and Nuclear Signaling
          
 
Synonyms
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            4EBP3; 4E-BP3