Anti-VAV2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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VAV2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-8F5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthetic peptide of human VAV2
Molecular Weight
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Calculated MW: 101 kDa; Observed MW: 101 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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7410
Uniprot ID
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P52735
Background
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Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian Vav proteins (Vav1, Vav2 and Vav3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed.
Research Area
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Signal Transduction
Synonyms
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VAV2; Vav 2 oncogene; VAV-2