Anti-DiMethyl-Histone H3 (Lys4) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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H3C1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100 ChIP: 1/20
Immunogen
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A synthesized peptide derived from human Methyl-Histone H3 (di K4)
Molecular Weight
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Calculated MW: 15 kDa; Observed MW: 15 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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8350
Uniprot ID
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P68431
Background
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H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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H3K4me2; H3 histone; HIST1H3A; Histone cluster 1; H3a