Anti-CD31 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
PECAM1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
BP6037
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC: 1/100-1/200
Immunogen
-
A synthesized peptide derived from human PECAM1
Molecular Weight
-
-
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
5175
Uniprot ID
-
P16284
Background
-
PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Research Area
-
Cardiovascular
Synonyms
-
Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31