Anti-CD163 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CD163
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/30
Immunogen
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A synthesized peptide derived from human CD163
Molecular Weight
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Calculated MW: 125 kDa; Observed MW: 150 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9332
Uniprot ID
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Q86VB7
Background
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Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner.
Research Area
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Immunology
Synonyms
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CD163; CD163 antigen; CD163 molecule; SCARI1; sCD163; Soluble CD163