Anti-ADRM1 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ADRM1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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5C3-L9-T6
Isotype
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IgG3/kappa
Reactivity
Application
Application Details
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WB：1/500-1/1000 IHC-P：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 42 kDa; Observed MW:42 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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11047
Uniprot ID
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Q16186
Background
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Proteasomal ubiquitin receptor ADRM1 is a protein that is encoded by the ADRM1 gene. It is a component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. ADRM1 engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation.
Research Area
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Signal Transduction
Synonyms
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Gp110, ARM-1, hRpn13