Anti-Acetyl Coenzyme A Carboxylase Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ACACB
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-2G8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthetic peptide of human Acetyl Coenzyme A Carboxylase
Molecular Weight
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Calculated MW: 277 kDa; Observed MW: 277 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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32
Uniprot ID
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O00763
Background
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Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage . May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1 .
Research Area
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Cell Biology
Synonyms
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ACC; ACAC; ACC1; ACCA; ACACAD