Anti-ABL(Y253H Mutant) Mouse Monoclonal Antibody

Anti-ABL(Y253H Mutant) Mouse Monoclonal Antibody
Anti-ABL(Y253H Mutant) Mouse Monoclonal Antibody
Anti-ABL(Y253H Mutant) Mouse Monoclonal Antibody
Anti-ABL(Y253H Mutant) Mouse Monoclonal Antibody

Anti-ABL(Y253H Mutant) Mouse Monoclonal Antibody

Mouse IgG Monoclonal for ABL1, ABL, JTK7, bcr-abl, c-ABL, p150, v-abl detection, Test with WB, IHC-P, ICC/IF, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ICC
  • IF
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07277
$680.00

Shipping To:
United States

Product Information

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Target
    ABL1, ABL, JTK7, bcr-abl, c-ABL, p150, v-abl
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    6O8-K2-O5
Isotype
    IgG
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ICC
  • IF
  • ELISA
Application Details
    ELISA: 1/1000-1/5000,WB: 1/100-1/1000,ICC/IF: 1/50-1/100,IHC-P: 1/50-1/100
Immunogen
    A synthetic peptide from the internal region of Abl which includes the mutation of Y253H, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1, is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, stress response and cell migration. Deficient in Abl can cause severe disease such as leukemia.
Research Area
    Signal Transduction
Synonyms
    ABL1, ABL, JTK7, bcr-abl, c-ABL, p150, v-abl
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Product Image

Western blot analysis of recombinant Abl(Y253H) and wild type proteins. Purified His-tagged Abl(Y253H) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-ABL(Y253H) mouse monoclonal.
Immunofluorescence of cells expressing Abl proteins with anti-Abl(Y253H).HEK293T cells were transfected with pCDNA3-GFP-Abl (WT) plasmid (left column) or pCDNA3-GFP-Abl(Y253H) plasmid (right column), then fixed and stained with anti-ABL(Y253H) monoclonal.