Anti-ABCA8 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ABCA8
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide corresponding to Human ABCA8.
Molecular Weight
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Calculated MW: 183kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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10351
Uniprot ID
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O94911
Background
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ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes by harnessing the energy of ATP hydrolysis. ABCA8 (ATP-binding cassette, sub-family A (ABC1), member 8) is a 1,581 amino acid multi-pass membrane protein that contains two ABC transporter domains and belongs to the ABC transporter family. Expressed in a variety of tissues with particularly high expression in liver, heart and skeletal muscle, ABCA8 functions as an ATP-dependent lipophilic drug transporter that exists as multiple alternatively spliced isoforms.
Research Area
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Synonyms
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ATP-binding cassette sub-family A member 8; KIAA0822