Anti-53BP1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TP53BP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-2B2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human 53BP1
Molecular Weight
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Calculated MW: 214 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7158
Uniprot ID
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Q12888
Background
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May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Tumor suppressor p53-binding protein 1; 53 BP1; p53-binding protein 1; p53BP1; TP53BP1; p53-BP1; p202