Anti-14-3-3 sigma Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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SFN
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-5C8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human 14-3-3 sigma
Molecular Weight
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Calculated MW: 28 kDa; Observed MW: 28 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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2810
Uniprot ID
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P31947
Background
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Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Research Area
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Neuroscience
Synonyms
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SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin